Primary Cutaneous Immunocytoma

Note: A Primary Cutaneous Immunocytoma (or Lymphoplasmacytoid Lymphoma) represents a low grade, B Cell Malignant Lymphoma, which is clinically distinct from a primary lymph node Immunocytoma, and classically not associated with Waldenstrom's Macroglobulinemia.

Microphotograph Series DSCN0294
Immunocytoma infiltrate in dermis, featuring sheets of plasmacytoid tumor cells with perinuclear hof spaces, H&E 400X
Primary Cutaneous Immunocytoma

Microphotograph Series DSCN0299.001
Immunoglobulin Polyclonal Kappa light chain special stain, displaying clonally restricted positive staining on all tumor cell perinuclear hof spaces, 400X
Primary Cutaneous Immunocytoma

Microphotograph Series DSCN0303
Immunoglobulin Polyclonal Lambda light chain special stain, displaying clonally restricted negative staining on all tumor cell perinuclear hof spaces, 400X

All photos were created by GDA staff members utilizing a Nikon Coolpix five megapixel color digital microphotography system. Photographs of selected additional case slides have been taken, and all images are available for review within the GDA slide library.